Publisher's Synopsis
Molecular Basis of Oxidative Damage by Leukocytes presents papers and many discussions from the First Montana State University/Keystone Symposium at Big Sky, Montana, January 28-February 2, 1991. The purpose of this meeting was to synthesize a molecular understanding of the creation, action, and interplay of the toxic oxygen species generated by leukocytes. The book covers a variety of aspects, including the molecular basis of superoxide generation by phagocytes, the major pathways of oxidative injury, events at the leukocyte superoxide generator/target interface, regulatory events that feed back to modulate leukocyte superoxide production, and the role of leukocyte oxidants in disease.
Audience will find a wealth of information in this one-of-a-kind book.