Publisher's Synopsis
This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1892 edition. Excerpt: ...act differently on these two species. In R. esculenta this alkaloid determines a paralysis of the motor nerves, and at the same time an increase in the excitability of the spinal cord. Of course, the influence on motor nerves prevents the spinal influence from being detected, unless the experiment is performed in a particular manner. In R. temporaria the symptoms are quite different; tetanic convulsions appear, and if the dose is considerable, motor paralysis ensues later. The case is the same with the common toad. 1 Cf. A. Chauveau: Sur les Proprittesvaccinalesde Microbes ci-devant tathogines transforms! en Microbes d"apparence saprogene. Archives de Medecine Experimental, March, 1889, p. 161. Also, by the same author: Rechtrches sur le Transformisme en Microbiologie pathogene. Des Limites, des Conditions et des Consequences de la Variability du Bacillus Anlhracis. Ibid. November, 1889, p. 757. 3 Archives des Sciences Physiques et Naturelles, Geneva, 1881. Similar facts had been witnessed years before by many physiologists. As early as 1864 my much regretted master Vulpianx found that the same poisons operate differently on the circulatory system of the two species. Two years afterwards J. L. Prevost2 witnessed facts confirmatory of the preceding, concerning the same animals when subjected to the influence of veratrin; the heart being arrested in one case, while it is merely slackened in the other. Then Schmie-deberg, in iS/4,3 took up the question, studying the influence of caffein, and saw that in R. temporaria caffein operates in determining a local action which gradually spreads a sort of muscular rigor, accompanied by a decrease in excitability; in R. esculenta there appear, on the contrary, an increase in excitability and tetanic...
