Publisher's Synopsis
In Autophagy-Induced Beta Amyloid Clearance in Alzheimer's Disease, Abubakar Wani provides a comprehensive overview of the role of autophagy in the clearance of beta-amyloid, a key pathological hallmark of Alzheimer's disease. The book presents the latest research and experimental evidence supporting the use of autophagy as a potential therapeutic target for the treatment of Alzheimer's disease.
The book begins with an overview of the cellular mechanisms of autophagy and its role in protein degradation, followed by a discussion of the pathophysiology of Alzheimer's disease and the role of beta-amyloid in disease progression. Wani then explores the molecular mechanisms by which autophagy can promote the clearance of beta-amyloid, including the regulation of autophagy by different signaling pathways and the role of autophagy in mediating the turnover of different protein aggregates.
The author also discusses the potential use of autophagy-inducing drugs as a therapeutic strategy for Alzheimer's disease, highlighting the current progress and challenges in the development of autophagy-targeting drugs. Additionally, the book covers the latest research on the role of autophagy in the clearance of other protein aggregates implicated in neurodegenerative diseases.
Overall, Autophagy-Induced Beta Amyloid Clearance in Alzheimer's Disease is a valuable resource for researchers, clinicians, and students interested in the molecular mechanisms underlying Alzheimer's disease and the potential therapeutic applications of autophagy induction. The book provides a comprehensive and up-to-date review of the latest research in the field, making it an essential reference for anyone working in this area.
