Publisher's Synopsis
A modern approach to the molecular biology and pharmacology of this prime target class for blockbuster drugs against depression and anxiety. Following an introduction, this handbook goes on to discuss such families as biogenic amine transporters, excitatory, inhibitory and heterodimeric amino acid transporters, before looking at the 3D structure of transporter targets. The final section on ligand–based approaches includes pharmacophore models as well as SAR and QSAR studies.
A comprehensive resource for medicinal chemists, neurophysiologists and pharmacologists alike.
