Publisher's Synopsis
This volume represents the comprehensive and definitive reference volume on cyclooxygenases 1 and 2 and their inhibitors. The whole field is covered from the basic science all the way through to the clinic. Several novel selective COX-2 inhibitors are now a liable and the publication coincides with an exciting stage in the development of therapeutic strategies using these drugs for the treatment of arthritis, pain and inflammation and their potential value for treatment of various cancers, Alzheimer's disease and premature labour. Each chapter is written by an acknowledged expert in the field, including the discoverers of COX-2 and the developers of the new drugs.