Publisher's Synopsis
Written by nearly two dozen of the world's foremost herpes virologists, this volume presents a review of all human herpesviruses identified to date. The book provides up-to-date information on the molecular biology of herpes simplex viruses, Epstein-Barr virus, cytomegalovirus, varicella-zoster virus, human herpesvirus 6 and 7, and B virus and the pathogenesis, pathology, epidemiology, diagnosis, treatment/prophylaxis, clinical course, and potential sequelae of the diseases these agents cause. Of special note are the detailed descriptions of state-of-the-art diagnostic techniques - such as tissue culture isolation, virus-specific antigen detection, viral nucleic acid detection, serologic responses, immunofluorescent and immunocytochemical techniques, enzyme-linked antibody techniques, restriction enzyme analysis, and PCR - and the timely discussions of current and evolving therapies such as immune globulins, antiviral agents, and HSV, EBV, CMV, and varicella vaccines.