Publisher's Synopsis
The riveting story of microglia-the "white blood cell of the brain"-from the scientists who discovered its amazing dual capabilities to harm and heal, to the cutting-edge treatments emerging for a wide variety of brain diseases, including alleviating depression and promising answers for Alzheimer's. Until recently, microglia were thought to be boring little brain housekeepers, helpfully pruning away dead cells. But science now understands them to have a terrifying Jekyl and Hyde control over brain health. When triggered, they morph into destroyers, causing a wide range of issues: from memory problems and anxiety to schizophrenia and Alzheimer's. Under the right circumstances, however, microglia are indeed angelic healers, making repairs in ways that reduce symptoms and, now that we understand their true role, could one day prevent disease. A riveting behind-the-scenes account of the science that identified microglia as our neurological immune system--"the most exciting discovery of the year" (Science, 2016)--The Angel and the Assassin also puts readers inside the promising medical implications; award-winning journalist Jackson Nakazawa (who herself has health issues explained by microglial behavior) follows three patients as they seek to reduce their neurological problems through new treatments. Giving new meaning to the mind-body connection and health cycle (emotional distress can become physical and physical disease impacts our emotional state), The Angel and the Assassin stands to change everything we thought we knew about how to heal our bodies, our brains, and regain our health.
