Publisher's Synopsis
Developed from a symposium sponsored by the Division of Physical Chemistry at the 207th National Meeting of the American Chemical Society, San Diego, California, March 13-18, 1994, this work provides comprehensive experimental and theoretical analyses of important organic reactions - Diels-Alder, Claisen and SN2 reactions. It also: examines equilibrium and nonequilibrium solvent effects for a variety of chemical processes; provides a comprehensive overview of the scope and utility of the present broad array of modeling techniques for mimicking aqueous solution; includes detailed studies of the hydrophobic effect as it influences protein folding and organic reactivity; and examines the effect of aqueous solvation on biological macromolecules and interfaces.