Publisher's Synopsis
This book provides a comprehensive introduction to the burgeoning serpin field to those unfamiliar with this family of proteins. It also serves as an invaluable reference book for all serpin investigators by containing both the most pertinent literature citations to individual serpins and to serpin structure and mechanism, and compilations of important and critically evaluated data on groups of serpins. The long-familiar antithrombin, plasminogen activator inhibitor-1, and heparin cofactor II, together with protein C inhibitor and proteinase nexin I, are considered from the perspective of their physiological activation by interaction with heparin and heparin-like molecules.
