Publisher's Synopsis
An evaluation of the design and findings of studies relevant to the safety assessment of selected food additives. It seeks to give toxicologists, the food industry, and regulatory agencies a record of the scientific evidence considered when the Committee allocates or revises acceptable daily intakes and other endpoints.;Emphasis is placed on studies that relate specific exposure levels to specific toxic effects or guide the meaningful extrapolation of animal data to the human condition. The book also demonstrates the safety standards used by JECFA in its efforts to protect consumers from any hazard linked to the use of food additives.;Separate toxicological monographs are presented for three flavouring agents, one food colour, one preservative, one sweetening agent, three thickening agents, and some miscellaneous substances. The second part of the report provides monographs on seven groups of related flavouring agents evaluated according to the Procedure for the Safety Evaluation of Flavouring Agents, and monographs summarizing the intake of five food additives.
