Publisher's Synopsis
SAR focuses on the quantitative structure-activity relationship (QSAR) of the disposition and activities of various pharmacological groups - the first systematic approach for linking different side effects of drugs to their molecular structure and physiochemical properties.
This unique monograph describes the application of molecular modification to the practical improvement of therapeutic agents; depicts the quantitative measurement of biological activity as it relates to QSAR; provides essential guidance on selecting suitable mathematical models, defining appropriate parameters in correlation studies and anticipating potential side effects during the tedious drug development process.
