Publisher's Synopsis
"Protein and Pharmaceutical Engineering" brings together a distinguished group of experts who scrutinize the architecture and activity of proteins to uncover the underlying principles of macromolecular form and function. Drawing on this knowledge, the contributors to this volume focus on designing and engineering proteins for the development of pharmaceuticals. The authors employ novel approaches in molecular genetics, enzymology, molecular modelling, NMR spectroscopy and X-ray crystallography to reveal the role primary amino acid sequence plays in protein structure and function. Chapters cover areas of research in two broad categories: physical analysis of protein structure and molecular biochemical aspects of protein function.
