Publisher's Synopsis
Explores the effects of physical forces on animal cell cultures in the two major contexts in which cell cultures are primarily used: as models in "in vivo" systems; and as production systems. A summary of the effects of physical forces on specific cell culture models of "in vivo" systems (endotheliel, skeletal, cardiac, smooth muscle, osteoblasts, osteoclasts, osteocytes and chondrocytes), is provided as a background for a discussion of general principles describing cellular responses to physical forces. The authors suggeest that in production systems utilizing cell cultures, physical forces may have specific biological effects in addition to the often emphasized destructive effects.
