Publisher's Synopsis
The subjects reviewed in this Monograph span a wide and exciting field, reflecting many different specialities. They are, however, also closely interrelated as they reflect the eclectic nature of Professor Paul Polani's intellectual interests. The chapters are written by present and past members of his Unit - a Unit internationally recognized for its astute and stimulating discoveries and innovations. The chapters pay tribute to the fact that Paul Polani's viewpoint is that a multidisciplinary approach to the subject of disease is most effective when motivated by genetic philosophy. On this theme the book provides insight into the latest ideas on the genetics of handicap - including counselling, population cytogenetics, prevention of biochemical genetic disorders, repairing genetic damage, the epidemiology of congenital defects, and the prevention of neural-tube defects. All these and the other chapters provide an essential basis for understanding the fields of prevention and treatment.
