Publisher's Synopsis
"Neural stem cells have the capacity to generate all of the multiple cell types found in the brain and spinal cord, thus, they have the potential to repair tissue injured by trauma or disease. The Guest Editors are researchers and clinicians who have done extensive work on human neural stem cells and the regeneration of neural cells in the brain. This issue of the Neurosurgery Clinics discusses embryonic and adult neural stem cells and their role in brain tumors, neurorestoration, trauma, and stroke.
Contents: 1. Embryonic human stem cells: Present and Future; Germinal Regions in the Adult Human Brain; Astrocytes as Adult Neural Stem Cells; Identification of Human Brain Tumor Initiating Cells; BMP-Mediated Therapeutic Targeting of Brain Tumor Stem Cells; Neural Precursors and Their Role in Medulloblastomas; PDGF-Mediated Gliomagenesis and Brain Tumor Recruitment; Stem Cells as Vehicles for the Treatment of Brain Cancer; Gene Chip Analysis of Epigenetic Stem Cell Remodeling; Glial Progenitors and Demyelinating Lesions; Adult Neurogenesis and Hippocampal Memory Function; Radiation Response of Neural Precursors; Injury following trauma or stroke; Regeneration of the Injured Spinal Cord; TBI-Related Effects on Neurogenesis; Neurogenesis after stroke: effects of growth factors.
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