Publisher's Synopsis
This concise, abundantly illustrated text provides a complete overview of multiple sclerosis for the internist, general neurologist and therapist. Including recent research findings in genetics, immunology and pathophysiology, the authors provide reliable and up-to-date guidance on the epidemiology, diagnosis, prognosis and treatment of MS. Of particular interest to neuroscientists and neurologists will be the reviews of experimental models of MS, pathology of the demyelinated plaque, HLA associations and the role of immune mechanisms. Environmental and geographical factors in the etiology of MS are examined, including the possible role of infectious agents. The clinical sections of the book include discussion of neurological, sexual, psychological and cognitive disturbances. Diagnostic criteria are reviewed, and rehabilitation measures are given special attention.
