Publisher's Synopsis
Significant progress in recent years of biochemical and epidemiological toxicology has led to the discovery of molecular targets and mechanisms of action of many environmental chemicals: and also to the development of knowledge on the biochemical changes to those exposed to a variety of environmental or occupational pollutants.;This book deals with the new indicators that are available in areas such as liver toxicity (enzyme induction and porphyrin metabolism), nervous system toxicity, nephrotoxicity and genotoxicity, as well as the measurement of toxic substances in human tissues. Each section covers an organ system or specific toxic effect, and is introduced by a state-of-the-art presentation by international scientists, who review the current basic knowledge, and critically assess the validity of the analytical methods involved. The authors discuss the usefulness and feasibility of introducing these indicators for health monitoring in various populations and for assessing subtle effects of exposure. Particular emphasis is given to the issues concerning interpretation of results and the areas for future research.
