Publisher's Synopsis
Tumours of the nervous system represent a difficult therapeutic challenge. During recent years, substantial progress has been made in characterizing genetic mechanisms involved in the formation of brain tumours. There is a lot of hope that an understanding of the molecular basis of transformation will eventually lead to specific therapeutic approaches.;In this volume, leading authorities in both molecular and clinical neuro-oncology summarize recent developments in their respective fields. The first part of the book will focus on specific molecular genetic defects in neural tumours and their potential clinical significance.;Part two gives an update on established and novel treatment regimens for patients with brain tumours. Several contributions will demonstrate that molecular and clinical neuro-oncology are already connected. With its unique combination of molecular biological and clinical data, this volume provides basic researchers and clinical neuroscientists with a comprehensive update in both disciplines.