Publisher's Synopsis
The goal of various professional disciplines that have for decades focused on insulin action is to elucidate the etiopathogenesis of diabetes mellitus. Since the late 1970s, a great deal of new knowledge on the mechanism of insulin action at the cellular and subcellular levels has accumulated. This has concentrated the attention of researchers on the role of the cell membrane and cellular organelles in influencing insulin-receptor interactions and on the genetic determinants of the structure and function of insulin receptors. New aspects of the mechanism of transmembrane insulin action have been revealed by exploiting the tools of molecular biology and by using contemporary immunological techniques. The amount aand depth of this data have intensified the need for an international exchange of information. This volume, in reporting the proceedings of the International Symposium in Insulin and the Cell Membrane, offers researchers and practicing physicians information on diabetes, receptor action and cell membrane function.