Publisher's Synopsis
Parkinson's disease (PD) is a progressive neurodegenerative disorder that affects movement. It is a progressive disease that affects the nervous system. The disease starts gradually, but as it progresses it has a significant impact on a person's movements. The disease may start with just a small tremor in the hand, but eventually, the tremors progress. Symptoms include slow movements, stiffness, loss of balance, difficulty standing up, and other uncontrollable movements. The problems with the movements occur because of changes in the brain. Parkinson's disease is a neurodegenerative disorder, which means that the brain is affected - specifically, the dopamine-producing neurons (also referred to as "dopaminergic" neurons) in a particular region of the brain called the substantia nigra. In other words, as the dopamine-producing cells deteriorate, the symptoms of Parkinson's disease grow worse.