Publisher's Synopsis
"Glycobiology" focuses on the synthesis and structure of protein and lipid-bound oligosaccharides. The book describes the mechanisms that cause these substances and carbohydrate-binding proteins to influence biological recognition and communication.;Informative chapters offer data on such topics as: the synthesis, structural characterization and biological functions of glycophosphoinositol lipids that are covalently attached to the carboxyl terminus of a variety of proteins and anchor the protein to the outer leaflet of the plasma membrane; the role of lectinlike molecules and carbohydrate receptors in cell-cell recognition events; the function of protein and lipid- glycosylation in such diseases as rheumatoid arthritis or chorionic carcinoma; the cloning of glycosyltransferases; and the concerns of pharmaceutical biotechnological companies (including drug targeting and recombinant protein expression) within this field.
