Formulating Poorly Water Soluble Drugs - AAPS Advances in the Pharmaceutical Sciences Series
Third edition
Hardback (20 May 2022)
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The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.
Book information
ISBN: | 9783030887186 |
Publisher: | Springer International Publishing |
Imprint: | Springer |
Pub date: | 20 May 2022 |
Edition: | Third edition |
DEWEY: | 615.19 |
DEWEY edition: | 23 |
Language: | English |
Number of pages: | 810 |
Weight: | 1433g |
Height: | 254mm |
Width: | 178mm |
Spine width: | 38mm |