Publisher's Synopsis
A manual that details the techniques of electrofusion and electroporation by researchers who were the first to show that the platelet membrane glycoproteins GP IIb and GP IIIa are associated in a complex. The interest in electrofusion was triggered by the potential of this technique to produce monoclonal antibodies with desired specificity in a more efficient way. Realizing the need for more information and together with Carl Borrebaeck, Inger Hagen arranged the First International Workshop on "Electrofusion in Hybriddoma Technology", Lysebu 1988.;This book aims to show how to produce monoclonal antibodies with improved electrofusion techniques, detailing protocols for electrofusion experiments with different cell fusion partners, describing the new electrofusion chamber allowing electrofusion with very few cells, and discussing the potential of directed electrofusion.
