Drug Safety in Pregnancy

This book combines the perspectives of clinical and laboratory medicine so as to present critically considered and practical information to the clinician concerning drug-induced injury to the human embryo and fetus. The information that has been included has been thoroughly and independently evaluated by the authors at source. Animal and pharmacokinetic data have been used when their relevance to the human situation is direct, or where they demonstrate important principles. Classical teratology syndromes, such as those caused by thalidomide or diethystilboestrol have been examined in some detail, even though the use of these agents in pregnancy no longer reflects contemporary practice. This has been done because they add an understanding of clinical teratology. "Drug Safety in Pregnancy" can be regarded as a companion book to Meyler's Side Effects of Drugs, and to the Side Effects of Drugs Annuals, and care has been taken to include material contained in recent editions of those volumes. The book provides a comprehensive and critical data base for any clinician, pharmacologist or research worker concerned with the safe use of medicines in the pregnant woman.