Drug Repurposing and Repositioning

Drug Repurposing and Repositioning Workshop Summary

Paperback (08 Aug 2014)

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Publisher's Synopsis

"Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs--a process referred to as drug repurposing or repositioning. Historically, drug repurposing has been largely an unintentional, serendipitous process that took place when a drug was found to have an offtarget effect or a previously unrecognized on-target effect that could be used for identifying a new indication. Perhaps the most recognizable example of such a successful repositioning effort is sildenafil. Originally developed as an anti-hypertensive, sildenafil, marketed as Viagra and under other trade names, has been repurposed for the treatment of erectile dysfunction and pulmonary arterial hypertension. Viagra gener

Book information

ISBN: 9780309302043
Publisher: The National Academies Press
Imprint: National Academies Press
Pub date:
DEWEY: 615.19
DEWEY edition: 23
Language: English
Number of pages: xxii, 96
Weight: 159g
Height: 226mm
Width: 150mm
Spine width: 8mm