Publisher's Synopsis
It is well known that the inbred NOD (non-obese diabetic) mouse is one of the excellent animal models for the study of insulin dependent diabetes in human subjects, with the NON (non-obese non-diabetic) mouse being selected only as the control strain. However, NON mice were found to show a defect in glucose tolerance and abnormality of the renal glomerulus, with further investigations suggesting that this strain may become a suitable animal model for either insulin dependent diabetes or renal dysfunction. This volume summarizes the reports on studies using NON mice in the first few years, reflecting the excellent fruition of the research within this field.
