Publisher's Synopsis
Reporting on the latest advances in molecular asymmetry, "Chirality and Biological Activity" explores the development of stereochemical analysis and its applications to the biosciences. Applications to pharmacology and therapeutics, food and beverage chemistry and the study of pesticides and other zenobiotics are also covered. The book looks into the molecular principles of chiral recognition and biological selectivity and discusses stereoselectivity in drug action and metabolism. Some of the specific issues covered include: gas and liquid chromatography of enantiomers on chiral stationary phases; stereochemical assays of chiral drugs; pyrethroid isomers; configurational modification of peptide hormones; chiral fruit flavours; and human pharmacokinetics of enantiomers administered as racemates.
