Publisher's Synopsis
A comprehensive treatment of the chemistry, biochemistry, pharmacology, and test methodology of drugs used to treat the major cardiac diseases. The book outlines the basic aspects of cardiac dysfuntion, giving an analysis of some common threads linking cardiac disease states, and provides specific information on screening methodology, including in vitro and whole animal models; extensive coverage of drug classes, including beta- adrenoceptor antagonists, calcium antagonists, antianginals, cardiotonic agents, and antiarrhythmic agents, and new cardiovascular drugs; and an analysis of the state of therapy for cardiac dysfunction and future directions for research and development.