Annual Reports in Medicinal Chemistry. V. 25 Academic Press Inc.,U.S - Annual Reports in Medicinal Chemistry S.

This volume marks the 25th anniversary of issues of "Annual Reports in Medicinal Chemistry". A continuing objective of this series has been to combine regular updates of significant areas of research in medicinal chemistry with emerging areas of biological science destined to make an impact on the future discovery and development of new medicinal agents.;Volume 25 retains the familiar format of previous volumes, this year with 35 chapters. Sections I-IV are related to specific medicinal agents, with annual updates on antipsychotics, antihypertensives, antiallergy agents, and antibacterials. Sections V and VI emphasize important emerging areas of medicinal chemistry and biology as well as the interface between these disciplines. Chapters in Section VI reflect the current focus on mechanism-directed drug discovery and newer technologies including PET, catalytic antibodies, and the interface between molecular biology and medicinal chemistry. Trends and perspectives (Section VII) is expanded from previous volumes with chapters on NCE introductions, stereochemistry and drug development, and concludes with a special chapter which provides a perspective on how 25 volumes of "Annual Reports in Medicinal Chemistry" have reflected the evolution of the field of medicinal chemistry over that same time period.