Publisher's Synopsis
Amiloride and Its Analogs Unique Cation Transport Inhibitors Edited by Edward J. Cragoe Jr. Thomas R. Kleyman Louis Simchowitz The rapidly growing interest in cation transport phenomena has captured the attention of chemists, biologists and medical scientists. Amiloride and certain of its analogs possess unique Na+–channel, Na+/H+–antiport, Na+/Ca2+–exchange and/or voltage–dependent Ca2+–channel inhibitory activity. This book reviews the extensive literature on the subject, puts the concept in perspective, reveals the applications, and regards the future of cation regulating agents in biological sciences and medicine.
