Publisher's Synopsis
The advances made in our understanding of the molecular structure and physiological function of the beta-and alpha-adrenoceptors have led to an additional appreciation of the roles that these receptors play in homeostasis and in pathological states. As a result, the beta-and alpha-adrenoceptor subtypes have become increasingly important drug targets due to their critical roles in the etiology, pathology and treatment of disease. This work reviews the current status of alpha-adrenoceptors from the standpoint of molecular biology, biochemistry and pharmacology.