Publisher's Synopsis
This volume offers a full account of the processes occurring in both the normal aging and pathological brain. Using a multidisciplinary approach, it covers biological and clinical investigations of brain function. It examines, in detail, epidemiological, clinical, biochemical, psychological, diagnostic and therapeutic aspects of aging brain and dementia.;The book offers vital studies of cerebral metabolism and function that link basic and clinical research. By applying such new technologies as PET, NMR and SPECT, experts can study biochemical and metabolic phenomena of the human brain. These studies not only underscore the cellular and subcellular phenomena occurring in the brain, but help establish a demarcation of a disease state from a normal state. Specifically, these new findings augment the knowledge of when an impairment of metabolism and of neurotransmission is still functional and therefore reversible and when it becomes morphological and irreversible.