Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide

Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide - Novartis Foundation Symposium

8th Edition

Hardback (20 Apr 2007)

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Publisher's Synopsis

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer's.

Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of alcohol dehydrogenase mutants, and the cell-signalling pathways implicated in alcohol-related pathology. It explores the mechanisms of acetaldehyde-induced damage to tissues, often a first step in carcinogenesis, including the oral cavity, the human airway, and the GI tract. The book considers pharmacological strategies and treatments for reducing oral and intestinal acetaldehyde. Acetaldehyde-Related Pathology features in-depth, round-table discussions by an international array of scientists from major laboratories worldwide involved in studies of acetaldehyde-related pathology.

This book is essential reading for anyone interested in the effects of this compound - pathologists, biochemists, toxicologists, cell and molecular biologists.

Book information

ISBN: 9780470057667
Publisher: Wiley
Imprint: John Wiley & Sons, Inc.
Pub date:
Edition: 8th Edition
DEWEY: 615.952
DEWEY edition: 22
Language: English
Number of pages: 275
Weight: 581g
Height: 236mm
Width: 158mm
Spine width: 20mm