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The Human Complement System in Health and Disease

The Human Complement System in Health and Disease

Hardback (25 Feb 1998)

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Publisher's Synopsis

This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases.
Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease

  • describes the molecular architecture of the complement system
  • details the structure of complement genes
  • discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins
  • analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway
  • elucidates the regulation of complement gene expression and the structure and function of bioactive peptides
  • explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria
  • and more!
  • Book information

    ISBN: 9780824798987
    Publisher: CRC Press
    Imprint: CRC Press
    Pub date:
    DEWEY: 616.0799
    DEWEY edition: 21
    Language: English
    Number of pages: 656
    Weight: 1361g
    Height: 254mm
    Width: 178mm
    Spine width: 36mm