Publisher's Synopsis
An up-to-date overview of the current status of research on the full scope of synaptic plasticity, including synaptic remodeling in response to damage, long-term depression and long-term potentiation, and learning and memory.Synaptic Plasticity presents an up-to-date overview of the current status of research on the full scope of synaptic plasticity, including synaptic remodeling in response to damage, long-term depression and long-term potentiation, and learning and memory. The contributions are written by leading experts in the field and cover approaches from biochemical, anatomical, physiological, behavioral, and computational levels. They offer hypotheses concerning the molecular and cellular mechanisms that are responsible for the various manifestations of synaptic plasticity and propose models explaining how these cellular events can be linked to the functional and behavioral expressions of these adaptive principles. ContentsIntroduction Molecular Correlates of Activity-dependent Development and Synaptic Plasticity, S. Hockfield Molecular Sorting in Neurons, 0. Steward Molecular and Morphological Responses to Deafferentation in Rodents, C. E. Finch, T. H. McNeill Forms of Long-term Potentiation Induced by NMDA and Non-NMDA Receptor Activation, T. Teyler, L. Grover Long-term Potentiation: Biochemical Mechanisms, M. Baudry, G. Lynch Cerebellar Mechanisms of Long-Term Depression, M. Ito Long-term Depression: Related Mechanisms in Cerebellum, Neocortex, and Hippocampus, A. Artola, W. Singer Theory of Synaptic Plasticity in Visual Cortex, N. Intrator, M. F. Bear, L. N. Cooper, M. A. Paradiso A Theoretical and Experimental Strategy for Realizing a Biologically Based Model of the Hippocampus, T. W. Berger et al Synaptic Plasticity, Learning, and Memory, S. P. Rose Synaptic Plasticity and Memory Storage, R. F. Thompson et al
