Publisher's Synopsis
The chapters of this book are grouped to provide a logical sequence for the reader. The first section, entitled Cell Types and Innervation Patterns brings together six presentations that address different aspects of the detailed anatomy of the dentate gyrus. Particular emphasis is placed on the three major cell types, granule cells, basket cells and the heterogeneous cells of the hilus. In addition, two of the chapters focus on the termination pattern of chemically-identified afferents to this region. The section concludes with a paper that bridges the gap between anatomy and the next section: Cellular Physiology and Functional Plasticity of neurons in the dentate gyrus. The five chapters in the second section are devoted to the electrophysiology of different neuronal types of the dentate gyrus. The middle section, entitled Seizures and the Regulation of Gene Expression and Protein Content , demonstrates some remarkable alterations in the expression of neuropeptides, growth factors and intracellular calcium-regulating proteins in experimental models of epilepsy.
