Publisher's Synopsis
Drugs in Context is an independent, peer reviewed and practice orientated review of all the significant data on a specific drug, placed in the context of the disease and clinical practice setting. Mirtazapine;;Editorial: "Not all patients with suicidal thoughts will communicate their feelings to their doctor. In addition, these thoughts may not be apparent at the time of consultation and may manifest before the medication becomes fully effective." Disease Overview: "Psychosocial stressors in later life, including the death or illness of a relative, marital problems, social isolation and adverse living conditions, play an important role in determining an individual's susceptibility to depression." Drug Review: "Mirtazapine therapy reduced the rate of remissive relapse by more than half, with 43.9 per cent of placebo-treated patients relapsing, compared with only 19.7 per cent of mirtazapine-treated patients." Improving Practice: "To improve the management of depression, it is vital that GPs have a good working knowledge of the condition, maintain a high index of suspicion, employ good consultation techniques and keep abreast of the latest information on the available treatment options."